Post-Acute Alcohol Withdrawal: Why Recovery Symptoms Can Continue After Alcohol Withdrawal

What To Know

  • Acute alcohol withdrawal and longer-term recovery are different phases.
  • Cravings, disturbed sleep, anxiety, irritability, reduced pleasure and difficulty concentrating can continue after the initial withdrawal period.
  • Symptoms and timelines vary considerably. Not everyone experiences PAWS, and there is no single pattern that applies to everyone.
  • PAWS is a useful descriptive term, but it is not a formal diagnosis with one agreed symptom list or timeline.
  • Continuing support after detox can make recovery safer and more manageable.

Important: Alcohol withdrawal can cause seizures, hallucinations, severe confusion and other life-threatening complications. If you drink heavily, drink every day, have experienced withdrawal before or are unsure about your risk, seek medical advice before stopping suddenly.

Alcohol recovery can be a challenging journey, and some of the most discouraging symptoms can continue after the acute withdrawal period has ended.

You may have stopped drinking, made it through the first difficult days and expected to feel steadily better. Instead, you may still be dealing with poor sleep, anxiety, irritability, cravings, low motivation or brain fog.

This does not necessarily mean that recovery is going badly. It usually means you are in the longer-lasting symptoms often described as post-acute withdrawal symptoms, post-acute withdrawal syndrome (PAWS) or protracted alcohol withdrawal.

In this article, we’ll dive into what PAWS is, the common symptoms of alcohol withdrawal and how we can best navigate it.

What Is Post-Acute Alcohol Withdrawal?

Acute alcohol withdrawal usually begins within hours after alcohol intake is stopped or substantially reduced. Symptoms can include sweating, tremor, nausea, anxiety, insomnia, a rapid heart rate and, is some more severe chronic cases, we can have seizures or delirium.

Post-acute alcohol withdrawal refers to symptoms that continue after this acute phase has settled.

The American Society of Addiction Medicine uses protracted withdrawal to describe symptoms such as anxiety, irritability and sleep disturbance that persist beyond the expected acute withdrawal period.

The term PAWS remains debated because it is not listed as a separate diagnosis in the DSM-5-TR or ICD-11. There is also no test that can confirm that a symptom is caused by PAWS.

Regardless, i’ll refer to it as PAWS, as essentially, it all ends up meaning the same thing.

Why Can Symptoms Continue After Alcohol Withdrawal?

Alcohol affects several systems involved in calmness, alertness, reward, sleep and stress. When we consume alcohol on a habitual basis, our brain adapts to alcohol becoming a need in our body.

As explained in Alcohol Withdrawal: The Seesaw Effect of Glutamate and GABA, alcohol strengthens inhibitory or slowing signals while suppressing excitatory signals. It’s purely a compensatory effect.

When we remove alcohol, the result is an overactive nervous system, which results in some of those more stimulatory symptoms such as anxiety, sleeplessness, etc.

The most dangerous parts of alcohol withdrawal pass within days, but then the bodies re-calibration or adaptation to no alcohol is where the other difficult symptoms arise.

Our stress signaling, reward processing, sleep architecture and cognitive function continue to change across the following weeks and even months.

Outside of brain chemistry, these symptoms are also impacted by our nutritional health, physical health, and other substances, living conditions and available support.

Common Symptoms During Longer-Term Recovery

Cravings That Gradually Diminish

Let’s set one thing straight first, Intense cravings are common during early abstinence.

Everyone encounters them in sobriety, but it’s often not a straight line when they come and go.

A craving can return suddenly when you are stressed, tired, around alcohol or reminded of an old drinking routine. Even an unexpected opportunity to drink can bring the urge back into focus.

A systematic review of protracted alcohol withdrawal found that craving generally declined across the first weeks and months, although individual experiences and treatment settings varied.

Alcohol cravings isn’t that we’re failing at all. It’s really just an older association to our previous bodies hardwiring. I discuss this further in Cravings 101: Understanding the Fundamentals of Why We Crave.

Impaired Stress Management

Irritability, increased sensitivity and difficulty managing stress are common complaints during extended abstinence.

Once normal ordinary demand sometimes feel more intense. The busy day after a poor nights sleep comes at us stronger than expected. This can be frustrating, particularly when you’re still in the earlier stages of quitting, you thought you’d feel calmer and have it all together, right?

Don’t worry, I did too, but actually stress is a common relapse trigger.

Learning how to recognise rising tension, reduce unnecessary pressure and ask for support is the important part.

The HPA Axis and Stress Sensitivity

The hypothalamic-pituitary-adrenal axis, usually shortened to the HPA axis, is one of the systems that coordinates the body’s response to stress.

Long-term alcohol use and repeated withdrawal can alter this stress-response system. Research reviewed in the PAWS literature suggests that stress signaling may remain disrupted during abstinence, which may contribute to negative mood, heightened stress sensitivity and difficulty coping in some people.

It doesn’t mean everyone is going to have a blunted HPA Axis, and it’s often also impacted by many other factors – Sleep, inflammation, workload and burnout.

The practical takeaway is that if your capacity for stress feels lower than usual, it’s actually useful information.

You have quit drinking alcohol, celebrate this as an achievement in itself and just reduce avoidable pressure where possible. Plan your stress free moments and build that stress management resilience back.

The HPA Axis can also be well supported by nutrients and herbal medicine, so please book a consultation and let me help be part of that stress management support!

Loss of Interest or Lowered Pleasure (Anhedonia)

Anhedonia means a reduced ability to feel interest, pleasure or reward.

Things you normally enjoy? They feel flat, you have difficulty getting motivated and staying motivated by ordinary daily activities.

This is particularly unsettling at any stage of recovery. Alcohol repeatedly activates reward pathways, and the brain can become less responsive to everyday rewards you may expect to give you that pleasure sensation. But it’s all normal during the recovery process.

The pleasure and motivation will return in time, assuming we’re supporting all the foundations of our health (sleep, diet, stress). Of course, persistent anhedonia can also coincide with depression and other health conditions. Do seek professional support if it is severe, worsening, accompanied by hopelessness or making it difficult to function.

Sleep Disturbance

Sleep can remain unsettled after the acute withdrawal period. You may struggle to fall asleep, wake repeatedly, experience vivid dreams or sleep for a long time without feeling refreshed.

Poor sleep also worsens irritability, anxiety, fatigue, cravings. It can be a hinging point where it escalates our stress and pushes us to the point of relapse.

It’s often caused by many factors, our neurochemicals re-balancing, our HPA Axis not functioning as it should. This is often why tailored support from a Naturopath is so beneficial, we can support all of this gently.

Putting into place regular sleep and wake times, morning light, and less stimulation at night can gently support our sleeps natural rhythm. More practical guidance is available in Sleep Hygiene: How To Reset Your Sleep and Circadian Rhythm.

Brain Fog and Cognitive Recovery

Brain fog can include difficulty concentrating, remembering information, planning, changing tasks or making decisions.

You’ve probably experienced it during that hangover stage, that brain “foggy” ness. It’s all part of the picture of our body re-balancing and re-calibrating.

This process can also take time. A 2024 systematic review found that many aspects of attention, executive function, perception and memory recovered over approximately six to twelve months of abstinence. Some abilities improved earlier, while a few showed more variable or slower recovery.

Fatigue

Fatigue is often related to the accumulation of the afforementioned symptoms. It’s tiring, our sleep is disrupted, our nervous system is working hard to regulate stress and a new everyday routine without alcohol.

It makes a lot of sense for us to be tired. You may also be doing it with kids or parenting, even worse (don’t worry, i’ve done it).

Alcohol can also be associated with nutritional deficiencies and a wide range of physical health problems. So some of this fatigue can come from long-term nutrient depletion.

Fatigue should not automatically be labelled as PAWS, particularly when it is severe or persistent.

How Long Does Post-Acute Withdrawal Last?

There is no reliable answer that applies to everyone, it’s a very individual process.

Some models describe it lasting three to six months or longer, but symptoms tend to not always follow the same timeline.

We may have eased cravings in the first month, while sleep, mood and other cognitive changes taking a little longer.

The duration and intensity is also impacted by:

  • How much and how long a person was drinking for.
  • Whether they have experienced repeated withdrawals or attempts to quit.
  • Other drug use or withdrawal.
  • Sleep and nutritional status.
  • Physical and mental health conditions.
  • Medications and treatment.
  • Current stress, safety and social support.

Symptoms may also appear to come in waves. A person may feel noticeably better, have several difficult days and then improve again. This can reflect stress, sleep loss, triggers or normal day-to-day function, which can also be an aggravating factor too.

Not All Of Your Symptoms Are Related

When we quit alcohol, it’s easy to bucket every uncomfortable symptom we have under the PAWS label.

Anxiety, depression, insomnia, fatigue, these may have been present before the drinking became severe. The can also be indicators of chronic health issues impacted by nutritional deficiency, hormone disruption, or other medical related conditions.

This isn’t me trying to minimise your sober journey, but a recommendation to organise a clinical review with a health professional when your symptoms are:

  • Severe, worsening or unexpected.
  • Persisting without improvement long-term.
  • Interfering with work, relationships or basic daily tasks.
  • Making it difficult to remain alcohol-free.
  • Accompanied by persistent low mood, panic or hopelessness.

During your journey, it’s always good to get support as well. This helps provide guidance and also ressurrance.

Long Term Recovery Support Tips

Useful longer-term support may include:

  • Ongoing support. To make it easier and ensure sufficient support, always seek help from your GP and other related health professionals. A Naturopath can also provide gentle support to really soften the impact of your symptoms too, while treating the root cause of something else.
  • Medication where appropriate. Some medications, such as Antabuse, may help for some people to maintain abstinence. This needs to be discussed with your GP.
  • A regular sleep rhythm. Keep wake time as consistent as possible, get morning light and reduce late-night stimulation.
  • Regular meals. Include adequate protein and a range of nutrient-dense foods. Nutritional deficiencies should be assessed and treated appropriately as well.
  • Gradual exercise. Walking, resistance training or another manageable form of movement can support sleep, mood and physical health. Build this habit gradually if you haven’t before so you’re not outrunning fatigue with intense training.
  • Stress regulation. Breathing exercises, quiet time, realistic workloads, time outdoors and structured relaxation can help lower the total stress load.
  • A plan for triggers. Identify the people, places, emotions and situations that increase risk. Recognising your triggers makes it easier to act before a craving becomes overwhelming.
  • Connection and accountability. Linking it back to the first point, support is important. Peer support, trusted friends, family, recovery groups and professional care can reduce isolation and make difficult periods easier to manage.

When To Get Professional Help

Speak with a GP or alcohol and other drug professional if symptoms are persistent, worsening, difficult to manage or increasing the risk of returning to alcohol.

Seek urgent medical care for seizures, hallucinations, severe confusion, chest pain, collapse, extreme agitation or a return of severe withdrawal symptoms. Call 000 if there is an immediate danger.

For free and confidential alcohol and other drug information in Australia, call the National Alcohol and Other Drug Hotline on 1800 250 015. The service directs callers to the relevant service in their state or territory.

If you are feeling overwhelmed, unsafe or unable to cope, contact Lifeline on 13 11 14. If life is in immediate danger, call 000.

The Bottom Line

Finishing alcohol withdrawal is an important step, but it is not always the point at which sleep, mood, stress tolerance and motivation immediately return to normal.

The process is not a straight line, so be patient with the process, and seek support always on the difficult days. Your body and brain are adjusting, so also be kind to yourself.

With time, appropriate care and support, your persistent symptoms will become less. It’s all a journey and a fulfilling life in recovery is achieveable!

If you need further support managing your symptoms or just after some gentle guidance, reach out for a free discovery call.

Frequently Asked Questions

Is post-acute withdrawal syndrome a recognised diagnosis?

PAWS is widely used as a descriptive term, but it is not a separate formal diagnosis in the DSM-5-TR or ICD-11. Researchers and clinicians may instead use terms such as protracted alcohol withdrawal or persistent symptoms during abstinence.

What are the most common symptoms after alcohol withdrawal?

Commonly reported symptoms include cravings, disturbed sleep, anxiety, irritability, reduced pleasure or motivation, fatigue and difficulty concentrating. These symptoms can have other causes, so persistent or severe problems should be assessed.

How long can symptoms continue after quitting alcohol?

There is no fixed PAWS timeline. Some symptoms improve over weeks, while sleep, mood or cognitive changes may continue for months. Drinking history, repeated withdrawals, health, other substances, stress and treatment can all influence recovery.

Why do the symptoms seem to come in waves?

Symptoms can become more noticeable after stress, poor sleep, conflict, skipped meals or exposure to drinking cues. Normal day-to-day variation can also make recovery feel uneven. A symptom wave does not necessarily mean that recovery has reversed.

Does having cravings mean recovery is failing?

No. Cravings are a common part of recovery and can return when an old cue or association is activated. The useful response is to identify the trigger, use your plan and seek support if cravings are becoming harder to manage.

Can the brain recover after long-term alcohol use?

Research indicates that meaningful recovery in many cognitive functions is possible with sustained abstinence. A systematic review found that many aspects of attention, memory and executive function recovered within six to twelve months, although recovery varied between individuals and cognitive abilities.

References

This article provides general information and is not a substitute for individual medical advice, diagnosis or treatment.

Alcohol Withdrawal: The Seesaw Effect of Glutamate and GABA

Article Snapshot (AI Generated)

  • Chronic alcohol use can create what I like to call the seesaw effect of glutamate and GABA.
  • The more heavily and regularly alcohol is used, the harder the brain may have to work to keep things balanced.
  • When alcohol is suddenly reduced or removed, the opposite effect can happen: the nervous system can become overstimulated.
  • This is one reason alcohol withdrawal can involve anxiety, shaking, sweating, insomnia, agitation and, in more serious cases, seizures or delirium.
  • Alcohol withdrawal can be medically serious. If you have been drinking heavily or for a long time, speak with a medical professional before stopping suddenly.

Chronic alcohol use creates what I like to call the seesaw effect of glutamate and GABA, and the more alcohol is used, the larger the swing can become.

When we wake up the next day, depending on the amount of alcohol consumed, we can often see the opposite of alcohol’s sedating effect.

Instead of relaxed, we feel anxious. Instead of sleepy, we feel wired.

Instead of calm, the nervous system feels like it has been turned up too high.

In this article, I’ll help you understand what alcohol withdrawal actually is, and unpack what’s known as the seesaw effect of glutamate and GABA.

Understanding Alcohol Withdrawal Symptoms

Alcohol withdrawal can happen when someone who has been drinking heavily or regularly suddenly stops drinking or significantly cuts down.

This is not the same as a standard hangover. A hangover is unpleasant, but alcohol withdrawal involves a nervous system that has adapted to alcohol and is now trying to function without it.

Common alcohol withdrawal symptoms may include:

  • anxiety
  • sweating
  • shaking or tremors
  • nausea or vomiting
  • poor appetite
  • poor sleep
  • increased heart rate
  • agitation or irritability
  • sensitivity to light, sound or stress
  • difficulty concentrating

More severe alcohol withdrawal can include seizures, hallucinations, severe confusion or delirium tremens. These symptoms require urgent medical care.

Alcohol withdrawal can also present as a potentially serious syndrome that can occur after abrupt cessation or reduction of heavy, sustained alcohol intake, with symptoms ranging from autonomic hyperactivity and tremor through to seizures and delirium in more severe cases (Jesse et al., 2017).

If you or someone else has severe confusion, seizures, hallucinations, chest pain, severe dehydration or looks seriously unwell, seek urgent medical help. In Australia, call 000 in an emergency. For non-emergency alcohol and drug support, the National Alcohol and Other Drug Hotline is 1800 250 015.

GABA and Glutamate

GABA and glutamate are two important neurotransmitters in the brain, and neurotransmitters are chemical messengers that help our nerve cells communicate.

GABA is generally inhibitory. It slows things down. It is associated with calm, relaxation, sleep and reduced nervous system activity.

Glutamate is generally excitatory. It speeds things up. It is involved in alertness, learning, memory and normal brain activation.

We need a tightly regulated balance of both, otherwise we may feel too sedated or hyper stimulated. Our body is always trying to maintain this balance.

This is where the seesaw analogy will come into play, we’ll discuss a bit more on this soon.

When both sides are balanced, the nervous system can respond appropriately. When one side is pushed too far, the body tries to compensate.

How Alcohol Affects GABA and Glutamate

Alcohol is a central nervous system depressant.

This means it can slow brain and nervous system activity. Part of this effect happens through GABA and glutamate.

Alcohol can increase GABA activity, which is one reason it may initially feel calming, sedating or relaxing. At the same time, alcohol can reduce glutamate activity, which further slows things down.

So, in simple terms:

  • GABA goes up
  • glutamate goes down
  • the nervous system becomes more sedated
  • We generally, feel pretty good!

The downside? Our brain doesn’t like being pushed out of balance.

When alcohol is used repeatedly, the brain starts compensating. It may reduce some GABA-related activity and increase glutamate-related activity to try to keep the nervous system functioning.

Chronic alcohol consumption creates neuroadaptive changes, including downregulation of GABA receptors and increased NMDA receptor expression, which is part of glutamate signaling (Haber & Lintzeris, 2021).

This is the body trying to restore that balance, and when we drink chronically, it’s almost a never ending cycle that worsens over time..

The Seesaw Effect

Think of alcohol as pushing down on one side of the seesaw. We first, experience the lovely, pleasant, sedating effects that come with it – Queue GABA.

When alcohol is removed after a good nights sleep, the sedating effect begins to dissipate.

The brains compensatory mechanics begin to kick in, and some level of anxiety, stimulation or uncomfortable…ness arises – Queue Glutamate.

This is why alcohol withdrawal can feel like the opposite of alcohol intoxication. Alcohol makes us feel relaxed, numb, sometimes sleepy. When we wake up the morning after, we start to feel more anxious, shaky, jittery, and wired..

StatPearls describes alcohol withdrawal as involving a relative reduction in GABA signaling alongside excess glutamate activity, contributing to the hyperactive state seen in withdrawal (Newman & Duby, 2024).

This does not mean every person will have severe withdrawal. It depends on the person’s drinking history, health, previous withdrawal episodes, medications, nutrition status and other factors.

The more we chronically indulge in repeated episodes of drinking though, the larger our seesaw swings, and the worse the symptoms become.

Why Alcohol Withdrawal Can Feel So Uncomfortable

When the nervous system is overstimulated, the symptoms can feel physical, mental and emotional, all at the same time.

Some key withdrawal symptoms you may see (or familiar with) include:

  • shaking hands
  • sweating
  • racing heart
  • nausea
  • poor sleep
  • anxiety
  • irritability
  • agitation
  • panic-like feelings
  • strong cravings

Most of these symptoms are our nervous system trying to recalibrate.

For some people, this process is uncomfortable but manageable with appropriate support. For others, it can become dangerous.

In individuals with severe alcohol withdrawal, this glutamate/GABA ratio gap can widen significantly (Brousse et al., 2012). If alcohol has been used heavily, daily, or for a long time, get medical advice before stopping suddenly.

That is why also to not guess your own risk level from just a simple blog post alone (Yes, even this one).

The Kindling Effect

Another important concept is kindling.

Kindling refers to the way repeated withdrawal episodes may make the nervous system more sensitive over time.

In practical terms, this means repeated cycles of heavy drinking, stopping, withdrawing and drinking again can sometimes make future withdrawal episodes more severe.

Repeated withdrawal experiences can progressively intensify withdrawal symptoms, and this includes an increased risk of seizure vulnerability (Becker, 2014).

It’s one reason why the stop-start cycle becomes so difficult. The swing is so great that we swing ourselves back to alcohol for comfort. We also just try do it alone, which when it comes to quitting alcohol, you should always get help.

For more on the wider neurochemistry involved in alcohol use and recovery, see Substance Abuse and Neurotransmitters: Understanding the Neurochemistry Behind Addiction and Sobriety.

Best Approaches for Alcohol Withdrawal

If you are drinking heavily or think you may be physically dependent on alcohol, the safest first step is to make it known to others.

This can be your loved one, friends, or other related family. You then need to get medical support; speak to your GP or related health professional before stopping suddenly.

This caveat is important here, because if you have been drinking for a long time, you can experience seizures and your life can be at risk.

Once you have spoken with a health professional for medical assessment/monitoring (and medication where appropriate) you can then look at habits, foundational nutrition, and ongoing peer support.

I would recommend looking at the articles below as well to support cravings and getting your foundations on track.

If you’re still unsure, please reach out or book a discovery call.

The Takeaway

Alcohol withdrawal is not simply a rough hangover. It can be the nervous system rebounding after adapting to regular or heavy alcohol use.

GABA and glutamate are only part of the picture, but they give us a useful way to understand why withdrawal can feel shaky, anxious, wired and physically intense.

The brain has been trying to keep the seesaw balanced. When alcohol is suddenly removed, the swing back can be uncomfortable and, for some people, dangerous.

If you are planning to reduce or stop heavy alcohol use, get medical guidance first. With the right support, withdrawal can be managed more safely, and the next stage of recovery can begin from a steadier place.

FAQ

Is alcohol withdrawal the same as a hangover?

No. A hangover usually follows a drinking episode and may include headache, nausea, fatigue and dehydration. Alcohol withdrawal occurs when someone who is physically dependent on alcohol reduces or stops drinking. It can involve nervous system overactivity and may become medically serious.

Why does alcohol withdrawal cause anxiety?

Alcohol can temporarily increase calming GABA-related activity and reduce excitatory glutamate-related activity. With repeated heavy use, the brain adapts. When alcohol is removed, the nervous system can rebound toward overactivity, which may feel like anxiety, agitation, poor sleep or internal restlessness.

Can alcohol withdrawal cause seizures?

Yes. Alcohol withdrawal can cause seizures in some people, especially when there is heavy long-term alcohol use, previous withdrawal seizures or other risk factors. This is one reason medical advice is important before stopping suddenly.

What is delirium tremens?

Delirium tremens, also called alcohol withdrawal delirium, is a severe form of alcohol withdrawal. It can involve confusion, agitation, hallucinations, tremor, unstable blood pressure and other serious symptoms. It is a medical emergency.

What should I do if I want to stop drinking?

Speak with a GP, addiction medicine clinician or alcohol and other drug service before stopping suddenly, especially if you drink heavily or daily. In Australia, you can call the National Alcohol and Other Drug Hotline on 1800 250 015. In an emergency, call 000.

References

Becker, H. C. (2014). Neurochemical mechanisms of alcohol withdrawal. Handbook of Clinical Neurology, 125, 133-156. https://pmc.ncbi.nlm.nih.gov/articles/PMC6943828/

Brousse, G., Arnaud, B., Vorspan, F., Richard, D., Dissard, A., Dubois, M., Pic, D., Geneste, J., Xavier, L., Authier, N., Sapin, V., Llorca, P.-M., De Chazeron, I., Minet-Quinard, R., & Schmidt, J. (2012). Alteration of glutamate/GABA balance during acute alcohol withdrawal in emergency department: A prospective analysis. Alcohol and Alcoholism, 47(5), 501-508. https://doi.org/10.1093/alcalc/ags078

Haber, P. S., & Lintzeris, N. (2021). Alcohol withdrawal. In P. S. Haber & B. C. Riordan (Eds.), Guidelines for the Treatment of Alcohol Problems (4th ed.). Specialty of Addiction Medicine, University of Sydney. https://alcoholtreatmentguidelines.com.au/chapter-8-alcohol-withdrawal

Jesse, S., Brathen, G., Ferrara, M., Keindl, M., Ben-Menachem, E., Tanasescu, R., Brodtkorb, E., Hillbom, M., Leone, M. A., & Ludolph, A. C. (2017). Alcohol withdrawal syndrome: Mechanisms, manifestations, and management. Acta Neurologica Scandinavica, 135(1), 4-16. https://pmc.ncbi.nlm.nih.gov/articles/PMC6084325/

Newman, R. K., & Duby, J. J. (2024). Alcohol withdrawal syndrome. StatPearls. https://www.ncbi.nlm.nih.gov/books/NBK441882/

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